This article examines guns, crime and social order in the West Indies. Set in the context of the region’s colonial history, contemporary geopolitics and the growing availability of small arms, the article analyses the extent and nature of gun homicide and related phenomena in various locations across the English-speaking Caribbean. It explores some explanations for the disturbing growth in violent death and injury mainly caused by guns, focusing specifically on the nexus between drug trafficking, political patronage and armed violence and the resulting `pistolizaton’ of civil society. The article examines the impact of extant security practices and offers some directions for future policy based on the precepts of public health, peace-building, violence prevention, gun control and the pursuit of human security.